杨金明

个人简介

职称：教授（博士生导师）

民族：汉族

学科专业：有机化学、药物化学

研究方向：1）药物化学导向的有机合成方法学研究；2）过渡金属催化合成反应；3）成环反应研究。

办公室：药学院13-428

电子邮箱：jmyang@scuec.edu.cn;yangjm1225@163.com

热忱欢迎有机化学、药物化学及相关专业优秀学生报考本课题组研究生，同时欢迎优秀的本科生加入课题组交流学习。

学习经历

2010.09-2015.06：华东理工大学，有机化学，理学博士（硕博连读），导师：施敏教授/研究员

2011.08-2015.06：中国科学院上海有机化学研究所，联合培养博士，导师：施敏教授/研究员

2006.09-2010.06：湖北大学，应用化学，理学学士

工作经历

2024.03-至今：中南民族大学，药学院，教授

2018.11-2024.03：中南民族大学，药学院，副教授

2016.06-2018.06：西班牙加泰罗尼亚化学研究所，欧盟“玛丽居里”学者计划(博士后项目)，导师：Antonio M. Echavarren教授

2015.07-2016.05：上海药明康德新药开发有限公司，管理培训生

承担项目与课题

（1）国家自然科学基金青年项目（No.22101303）2022-2024主持

（2）湖北省自然科学基金面上项目（No.2023AFB664）2023-2025主持，结题“优秀”

（3）中央高校基本科研业务费专项资金重点项目（No.CZZ24006）2024-2026主持

（4）中南民族大学引进人才科研启动基金重点项目（No.YZZ18009）2019-2023主持，已结题

（5）科技部外国文教专家项目（No.G2022185002L）2022.1-2023.12主持，已结题

（6）湖北省自然科学基金面上项目（No.2020CFB250）2020-2022主持，已结题

（7）科技部外国文教专家项目（No.G20200017117）2020.1-2020.12主持，已结题

（8）中央高校基本科研业务费专项资金项目（No.CZQ19014）2019-2020主持，已结题

（9）欧洲研究理事会（ERC）“玛丽居里”学者计划（No.702524）2016-2018主持，已结题

主要获奖及荣誉

2026年“优秀共产党员”

2025年第八届“十佳青年教工”

2024-2025学年度“五四青年（教工）先锋”

2021-2022学年“优秀班导师”

2018年中南民族大学“海外优秀人才”引进

2018年入选湖北省高层次人才计划

2016年入选欧盟“玛丽居里”学者计划

2014年获得博士研究生国家奖学金

学术兼职

中国化学会/美国化学会会员，受邀担任国际学术期刊Organic Letters、Chemical Communications、Advanced Synthesis & Catalysis、The Journal of Organic Chemistry、Bioconjugate Chemistry、Current Topics in Medicinal Chemistry、Current Organic Chemistry审稿人。

论文成果

(1)Xiang Huang,Jin-Ming Yang.*Lewis Acid-Catalyzed Intramolecular Cyclization of 7-Alkynylcycloheptatrienes with Carbonyls: Access to 3,4-Disubstituted 2,5-Dihydropyrroles.Chemical Communications,2025,61, 9686-9689.(SCI二区期刊，Nature指数收录)

(2)Ze Zhou, Xiang Huang, Qing-Yi Wei, Yi-Lin Wang, Bin Wu,Jin-Ming Yang.*. Access to Piperazine-Fused Pyrrolocarbazoles Enabled by Acid-Catalyzed Stereoselective Hydroarylation of Ynamide-Indoles and Subsequent Diels-Alder Reactions/Aromatizations.Organic Letters,2024,26, 7273-7278. (SCI一区top期刊，Nature指数收录)

(3)Jin-Ming Yang,*Guang-Chao Feng, Xiang Huang, Yi-Lin Wang, Qing-Yi Wei, Bin Wu.* Rhodium(III)-Catalyzed Intramolecular Cyclization and Sequential Aromatization of Ynamides with Propargyl Esters: Access to 2,5-Dihydropyrroles and Pyrroles.Organic Letters,2024,26, 6191-6196. (SCI一区top期刊，Nature指数收录)

(4)Xin-Yu Yang,^§Jin-Ming Yang,^§*Bin Wu.* TMSOTf-Promoted Cyclization of Indole-2-methyl-a-aminoketones: Access to 4-Aryl-Substitutedb-Carbolines.Organic Letters,2024,26, 1105-1109. (§共同一作，SCI一区top期刊，Nature指数收录)

(5)Guang-Chao Feng,^†Jun-Chi Li,^†Xiang Huang, Ji-Kai Liu, Bin Wu,Jin-Ming Yang.*Cascade Hydroarylation/Diels-Alder Cycloaddition of Alkynylindoles with Electron-Deficient Alkynes and Alkenes.Chemical Communications,2024,60, 328-331.(†共同一作，SCI二区top期刊，Nature指数收录)

(6)Qing-Yi Wei,^†Ze Zhou,^†Meng-Lian Yao,^†Ji-Kai Liu, Bin Wu,Jin-Ming Yang.*Rhodium(III)-Catalyzed Intermolecular [3+3] Annulation of Benzoxazines with Quinone Compounds: Access to Spiro-Heterocyclic Scaffolds.Chemical Communications,2023,59, 11520-11523.(†共同一作，SCI二区top期刊，Nature指数收录)

(7)Meng-Lian Yao, Xiao-YuanWang, Guang-Chao Feng, Ji-Kai Liu, Bin Wu,*Jin-Ming Yang.*Palladium(II)-Catalyzed Intramolecular [2 + 2 + 2] Annulation of Indolyl 1,3-Diynes: Construction of Azepino-Fused Carbazoles.Organic Letters,2023,25, 4615-4620. (SCI一区top期刊，Nature指数收录)

(8)Jin-Ming Yang,*Meng-Lian Yao, Jun-Chi Li, Ji-Kai Liu, Bin Wu.* Access to Azepino-annulated Benzo[c]carbazoles Enabled by Gold-Catalyzed Hydroarylation of Alkynylindoles and Subsequent Oxidative Cyclization.Organic Letters,2022,24, 6505-6509. (SCI一区top期刊，Nature指数收录)

(9)Zhe Fan,^{^}Shao-Fei Ni,^{^}Jin-Yu Pang, Li-Ting Guo, Hao Yang, Ke Li, Cheng Ma, Ji-Kai Liu,* Bin Wu,*Jin-Ming Yang.*Cu(I)-catalyzed cross-coupling rearrangements of terminal alkynes with tropylium tetrafluoroborate: Facile access to barbaralyl substituted allenyl acid esters and 7-alkynyl cycloheptatrienes.The Journal of Organic Chemistry,2022,87, 3066-3078. (SCI二区top期刊)

(10)Inmaculada Martín-Torres, Gala Ogalla,Jin-Ming Yang, Antonia Rinaldi, Antonio M. Echavarren*.Enantioselective alkoxycyclization of 1,6-enynes with gold(I)-cavitands: Total synthesis of Mafaicheenamine C.Angewandte Chemie International Edition,2021,60, 9339-9344. (SCI一区top期刊，Nature指数收录，入选Top Downloaded Article，IF2021: 15.336)

(11)Jin-Ming Yang, Cheng-Zhi Zhu, Xiang-Ying Tang,* Min Shi*.Rhodium(II)-catalyzed intramolecular annulation of 1-sulfonyl-1,2,3-triazoles with pyrrole and indolerings: facile synthesis ofN-bridgehead azepineskeletons.Angewandte Chemie International Edition,2014,53, 5142-5146. (SCI一区top期刊，Nature指数收录，入选ESI高引用论文，已引用163次，IF2014: 11.261)

(12)Jin-Ming Yang, Peng-Hua Li, Yin Wei, Xiang-Ying Tang,* Min Shi*.Gold(I)-catalyzed highly stereoselective synthesis of polycyclic indolines: construction of four contiguous stereocenters.Chemical Communications,2016,52,346-349.(SCI一区top期刊,Nature指数收录)

(13)Jin-Ming Yang, Xiang-Ying Tang,* Min Shi*.Gold(I)-catalyzed intramolecular cycloisomerization of propargylic esters with furan rings.Chemistry – A European Journal,2015,21, 4534-4540. (SCI二区top期刊)

(14)Jin-Ming Yang,Xiang-Ying Tang,Yin Wei,*Min Shi*.Phosphine-promoted cyclization of dicyclopropenones.Advanced Synthesis & Catalysis,2013,355, 3545-3552.(SCI二区top期刊)

(15)Jin-Ming Yang,Zhen Zhang,Yin Wei,*Min Shi*.Silver(I)-catalyzed tandem reactions ofN-activated aziridine-propargylicestersto pyrrolidin-3-one derivatives.TetrahedronLetters,2012,53, 6173-6176.(SCI三区)

(16)Jin-Ming Yang,Rui Zhang, Wen-Feng Wang, Zhen Zhang,Min Shi*.Axially chiralN-heterocyclic carbenegold(I) complex catalyzed asymmetricFriedel-Crafts/cyclization reaction of nitrogen-tethered 1,6-enynes withindole derivatives.Tetrahedron Asymmetry2011,22, 2029-2038.(SCI三区)

(17)Wen-Feng Wang,Jin-Ming Yang,Fei-Jun Wang,Min Shi*.Axially chiralN-heterocyclic carbenegold(I) complex catalyzed asymmetric cycloisomerization of 1,6-enynes.Organometallics2011,30, 3859-3869.(SCI二区)

(18)Peng-Hua Li,Jin-Ming Yang, Yin Wei,*Min Shi*. Silver(I)-catalyzed intramolecular cyclizations of epoxide-propargylic esters to 1,4-oxazine derivatives.ChemistryOpen2017,6, 21-24. (SCI三区)

专利

(1)杨金明，姚梦莲，吴滨，一种稠环吲哚类化合物及其制备方法和应用，授权日期：2024.02.27，授权专利号：ZL202210679227.8，发明专利，中国。

(2)杨金明，李俊驰，一种稠环氢化异喹啉化合物及其制备方法和应用，申请号或专利号：202310955290.4，申请日期：2023.7.31，发明专利，中国。